Application Effectiveness of Hierarchical and Classified Management of Antimicrobial Drugs in a Hospital
Objective To promote the rational use of antimicrobial drugs in clinical practice.Methods The data related to the application of antimicrobial drugs before and after hierarchical and classified management in the Hospital Information System were collected and compared.Hierarchical management included three steps including first personalized management,middle real-time management and final targeted management.The departments were divided into key departments,sub-key departments and general departments in the classified management.Results Compared with those before management(January to June 2022),the antibiotics use density(AUD)in the hospital decreased from 44.27 to 38.37 after management(July to December 2022),and showed a decreasing trend overally;the defined daily doses(DDDs)decreased from 228 302.53 to 189 493.16,the drug with the most significant change in DDDs was the Morinidazole and Sodium Chloride Injection with a decrease of 65.50%,and cephalosporins and nitroimidazoles showed a significant decrease in DDDs.Compared with those before management,the usage rate of antimicrobial drugs decreased from 38.31%to 36.03%,the proportion of antimicrobial drugs decreased from 12.33%to 10.80%,the proportion of combined use of antimicrobial drugs decreased from 25.20%to 19.46%,and the duration of anti-infection treatment shortened from(7.38±0.05)d to(6.83±0.05)d.Compared with those before management,the average length of hospital stay of patients significantly shortened,the consumption sum of antimicrobial drugs significantly decreased,and the submission rate of etiological specimens significantly increased(P<0.05).Conclusion Strengthening the antimicrobial stewardship can improve the compliance rate of clinical physicians in the relevant technical specifications and promote the rational use of antimicrobial drugs in clinical practice.
antimicrobial drughierarchical and classified managementrational drug usepharmaceutical care
万方数据
维普
