Efficacy Evaluation of Autologous Serum Combined with Pranoprofen in the Treatment of Dry Eye Syndrome After Implantable Collamer Lens
Objective To investigate the clinical efficacy of autologous serum combined with pranoprofen in the treatment of dry eye syndrome after implantable collamer lens(ICL).Methods A total of 110 patients with dry eye syndrome after ICL admitted to the hospital from January 2019 to May 2022 were selected and divided into the observation group and the control group based on different medication regimens,with 55 cases in each group.The patients in the two groups were given Pranoprofen Eye Drops,on this basis,the patients in the observation group were given autologous serum.Both groups were treated continuously for three months.Results The total effective rate in the observation group was 98.18%,which was significantly higher than 80.00%in the control group(P<0.05).Compared with those in the control group,the tear film break-up time(BUT)in the observation group significantly prolonged,the tear secretion length significantly increased at the one and three months of treatment(P<0.01).The corneal fluorescein staining score at the two and three months of treatment and dry eye syndrome score at the one,two and three months of treatment in the observation group significantly decreased(P<0.05).After treatment,the interleukin-1β(IL-1β),interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α)levels in the observation group significantly decreased,and the quality of life score significantly increased(P<0.05).The proportion of patients with normal perception after treatment in the observation group was 85.45%,which was significantly higher than 67.27%in the control group(P<0.05).Conclusion Autologous serum combined with pranoprofen can effectively relieve the inflammatory reactions of eyes and improve symptoms of dry eye syndrome in patients after ICL.
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