Molecular Mechanism and Clinical Research Progress of Vitamin K in the Treatment of Neurodegenerative Diseases
Objective To summarize the molecular mechanism and clinical research progress of vitamin K in the treatment of neurodegenerative diseases.Methods Literature analysis method was used to search literature related to vitamin K in the treatment of neurodegenerative diseases in the PubMed and CNKI databases from their inception to February 2024.The molecular mechanism of vitamin K in the treatment of neurodegenerative diseases was sorted out in terms of protein misfolding,mitochondrial dysfunction,oxidative stress,neuroinflammation,and ferroptosis.Results and Conclusion Vitamin K can improve mitochondrial function,reduce the incidence of oxidative stress,neuroinflammation,and ferroptosis,and reverse the pathological process of neurodegenerative diseases in cells or animal models by affecting the regulation of protein aggregation and autophagy.
国家科技期刊平台
NSTL
万方数据
