Rationality Evaluation of Proton Pump Inhibitors in the Prevention of Stress Ulcers During the Perioperative Period in a Hospital
Objective To evaluate the rationality of the use of proton pump inhibitors(PPIs)in the prevention of stress ulcers(SU)in surgical patients during the perioperative period in a hospital,and to provide a reference for the rational use of PPIs in the clinic.Methods A total of 213 medical records of discharged patients who received prophylactic use of PPIs during the perioperative period from October to December 2022 were randomly selected from the surgical department of the hospital.The general data of the patients,surgical status,existence of stressors,risk factors,and use of PPIs were collected and analyzed,and the rationality of the use of PPIs was evaluated according to guidelines and drug instructions.Results Among 213 patients,229 cases had irrational use of PPIs.Among them,132 cases(57.64% )had no indication for prophylactic medication,50 cases(21.84% )had inappropriate administration frequency,23 cases(10.04% )had inappropriate administration routes,16 cases(6.99% )had inappropriate administration timing,and 8 cases(3.49% )had a prolonged course of PPIs for prophylaxis.Conclusion When using PPIs to prevent SU in surgical patients during the perioperative period,there are unreasonable phenomena such as irrational medication indications,and administration frequency and administration routes.Clinicians,clinical pharmacists,and hospital quality management departments should attach great importance to it,establish medication standards of PPIs for the prevention of surgical patients with SU during the perioperative period,and standardize the use of PPIs during the perioperative period.
国家科技期刊平台
NSTL
万方数据
