Clinical Practice of Deprescribing Intervention in Polypharmacy for Elderly Patients
Objective To provide a reference for carrying out the deprescribing-related research and clinical practice in China.Methods The current research status and evidence of deprescribing at home and abroad was elaborated,the main reference tools and process of deprescribing were summarized,and a specific case of hospital pharmacists intervening in polypharmacy for elderly patients based on deprescribing was shared.Results Through a series of deprescribing practices,foreign countries had formulated various processes and guidelines that can guide deprescribing in different situations,while the related research started relatively late in China,but the development trend was good.The domestic and foreign research evidence and pharmacists' clinical practice in deprescribing(the patient was given eight basic medications,and he had a good adherence with five of them;the drugs involving deprescribing included glimepiride,amitriptyline,rabeprazole,estazolam)showed that deprescribing intervention for elderly patients in polypharmacy was safe and feasible.Conclusion Deprescribing is a scientific medication management mode based on evidence-based medicine,which can be as an important measure to intervene in polypharmacy for elderly patients.
deprescribingelderly patientpolypharmacypotentially inappropriate medicationclinical practice