首页|"处方精简"干预老年患者多重用药的临床实践

"处方精简"干预老年患者多重用药的临床实践

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目的 为我国开展处方精简相关研究和临床实践提供参考.方法 阐述国内外处方精简研究现状及精简证据,总结处方精简主要参考工具,并归纳处方精简流程,分享医院药师基于处方精简干预老年患者多重用药的具体案例.结果 国外已通过一系列处方精简实践,制订了多种可用于不同情况下指导处方精简的流程和指南,我国相关研究起步较晚,但发展趋势良好.国内外研究证据及药师的处方精简临床实践(患者基本用药共 8 种,其中 5 种用药依从性较好;涉及处方精简药物包括格列美脲、阿米替林、雷贝拉唑、艾司唑仑)均表明,处方精简干预老年患者多重用药安全、可行.结论 处方精简是基于循证医学的科学用药管理模式,可作为干预老年患者多重用药的重要措施.
Clinical Practice of Deprescribing Intervention in Polypharmacy for Elderly Patients
Objective To provide a reference for carrying out the deprescribing-related research and clinical practice in China.Methods The current research status and evidence of deprescribing at home and abroad was elaborated,the main reference tools and process of deprescribing were summarized,and a specific case of hospital pharmacists intervening in polypharmacy for elderly patients based on deprescribing was shared.Results Through a series of deprescribing practices,foreign countries had formulated various processes and guidelines that can guide deprescribing in different situations,while the related research started relatively late in China,but the development trend was good.The domestic and foreign research evidence and pharmacists' clinical practice in deprescribing(the patient was given eight basic medications,and he had a good adherence with five of them;the drugs involving deprescribing included glimepiride,amitriptyline,rabeprazole,estazolam)showed that deprescribing intervention for elderly patients in polypharmacy was safe and feasible.Conclusion Deprescribing is a scientific medication management mode based on evidence-based medicine,which can be as an important measure to intervene in polypharmacy for elderly patients.

deprescribingelderly patientpolypharmacypotentially inappropriate medicationclinical practice

董燕燕、徐鹏、伍超、车富强、陈震

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安徽医科大学合肥第三临床学院·安徽省合肥市第三人民医院,安徽 合肥 230022

安徽中医药大学第一附属医院·安徽省中医院,安徽 合肥 230011

处方精简 老年患者 多重用药 潜在不适当用药 临床实践

安徽省合肥市第三人民医院科研项目安徽中医药大学临床科研项目

SYKY2019182021yfylc11

2024

中国药业
重庆市食品药品监督管理局

中国药业

CSTPCD
影响因子:1.369
ISSN:1006-4931
年,卷(期):2024.33(14)
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