Effect of Shaoma Zhijing Granules Combined with Ear Point Pressing Beans on the Symptom Improvement and Trace Element Levels in Children with Tic Disorder
Objective To investigate the effect of Shaoma Zhijing Granules combined with ear point pressing beans on symptom improvement and trace element levels in children with tic disorder.Methods A total of 80 children with tic disorder admitted to The First People's Hospital of Zhaoqing City from January 2022 to March 2023 were selected and randomly divided into the observation group and the control group,with 40 cases in each group.The children in the two groups received oral administration of Thipride Hydrochloride Tablets,on this basis,the children in the observation group were treated with Shaoma Zhijing Granules combined with ear acupoint pressing beans.Both groups were treated continuously for eight weeks.Results The total effective rate in the observation group was 95.00%,which was significantly higher than 65.00%in the control group(P<0.05).After treatment,the Yale Global Tic Severity Scale(YGTSS)score,each traditional Chinese medicine syndrome score,the levels of lead(Pb),norepinephrine(NE),and dopamine(DA)in the observation group were significantly lower than those in the control group(P<0.05),while the levels of brain-derived neurotrophic factor(BDNF),zinc(Zn),and iron(Fe)in the observation group were significantly higher than those in the control group(P<0.05).Conclusion Shaoma Zhijing Granules combined with ear acupoint pressing beans has good clinical efficacy in the treatment of children with tic disorders,which can improve clinical symptoms,and regulate neurotransmitter and trace element levels.
Shaoma Zhijing Granulesear acupoint pressing beanschildren with tic disorderstraditional Chinese medicine syndrometrace elementsneurotransmitters
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