Effect of Yangyuan Jiangu Decoction Combined with Routine Calcium Supplementation on Bone Mineral Density and Fracture Healing Speed in Elderly Patients with Intertrochanteric Fracture After Intramedullary Nail Surgery
Effect of Yangyuan Jiangu Decoction Combined with Routine Calcium Supplementation on Bone Mineral Density and Fracture Healing Speed in Elderly Patients with Intertrochanteric Fracture After Intramedullary Nail Surgery
Objective To investigate the effect of Yangyuan Jiangu Decoction combined with routine calcium supplementation on bone mineral density and fracture healing speed in elderly patients with intertrochanteric fracture after intramedullary nail surgery.Methods A total of 90 elderly patients who underwent intramedullary nail surgery for intertrochanteric fracture of the femur admitted to the hospital from January 2018 to February 2022 were selected and divided into the routine calcium supplementation group and the Yangyuan Jiangu Decoction group by the random number table method,with 45 cases in each group.The patients in the two groups were treated with routine calcium supplementation after surgery,while the patients in the Yangyuan Jiangu Decoction group received additional treatment with Yangyuan Jianggu Decoction.Both groups were treated for one month.Results The total effective rate in the Yangyuan Jiangu Decoction group was 93.33%,which was significantly higher than 73.33%in the routine calcium supplementation group(P<0.05).After treatment,the content of bone metabolism indexes such as β-collagen degradation products(β-CTX)in the two groups significantly decreased(P<0.05),while the levels of procollagen typeⅠamino terminal peptide(PⅠNP)and serum osteocalcin(OC)in the two groups significantly increased(P<0.05),and those in the Yangyuan Jiangu Decoction group were significantly better than those in the routine calcium supplementation group(P<0.05).The Harris Hip Scale(HHS)score and bone mineral density(BMD)in the two groups significantly increased(P<0.05),and those in the Yangyuan Jiangu Decoction group were significantly higher than those in the routine calcium supplementation group(P<0.05).The femoral fracture healing time in the Yangyuan Jiangu Decoction group was significantly shorter than that in the routine calcium supplementation group(P<0.05).The incidence of adverse reactions was comparable between the Yangyuan Jiangu Decoction group and the routine calcium supplementation group(6.67%vs.4.44%,P>0.05).Conclusion Yangyuan Jiangu Decoction combined with routine calcium supplementation has good efficacy and safety in the treatment of elderly patients with intertrochanteric fractures after intramedullary nail surgery,which can increase the patient's BMD and fracture healing speed.
关键词
养元健骨汤/常规补钙/股骨骨折/髓内钉术/骨密度/骨折愈合速度
Key words
Yangyuan Jiangu Decoction/routine calcium supplementation/femoral fracture/intramedullary nail surgery/bone mineral density/fracture healing speed