Clinical Evaluation of Zhuyu Zhitong Decoction in the Treatment of Lumbar Disc Herniation
Objective To investigate the clinical efficacy of Zhuyu Zhitong Decoction in the treatment of lumbar disc herniation.Methods A total of 100 patients with lumbar disc herniation admitted to the hospital from January 2020 to January 2022 were selected and divided into the control group and the observation group by the random number table method,with 50 cases in each group.The patients in the two groups received routine conservative treatment(including rest on bed,continuous traction,symptomatic treatment),on this basis,the patients in the observation group received Zhuyu Zhitong Decoction.Both groups were treated for one month.Results The total effective rate in the observation group was 96.00%,which was significantly higher than 84.00%in the control group(P<0.05).After treatment,the traditional Chinese medicine(TCM)syndrome score,Oswestry disability index(ODI)score,Visual Analogue Scale(VAS)score,prostaglandin E2(PGE2),substance P(SP),dopamine(DA),interleukin-6(IL-6),interleukin-1β(IL-1β),C-reactive protein(CRP),tumor necrosis factor-α(TNF-α)levels in the two groups significantly decreased;the Japanese Orthopaedic Association(JOA)score in the two groups significantly increased;and the above indexes in the observation group were significantly better than those in the control group(P<0.01).The incidence of adverse reactions in the observation group was similar to that in the control group(4.00%vs.8.00%,P>0.05).Conclusion Zhuyu Zhitong Decoction can improve the lumbar vertebra function,relieve pain,and alleviate inflammatory reactions in patients with lumbar disc herniation.
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