Risk Factors for Infection After Meningioma Resection Based on Propensity Score Matching
Objective To investigate the risk factors for infection after meningioma resection.Methods A total of 288 patients who underwent meningioma resection in the hospital from January 2020 to December 2021 were selected and retrospectively analyzed.They were divided into the infected group(91 cases)and the uninfected group(197 cases)based on whether postoperative infection occurred.The two groups were matched at 1∶1 by the propensity score matching(PSM)method.The independent risk factors for infection after meningioma resection were evaluated by the Logistic regression model.Results A total of 61 pairs of patients were successfully matched.The Logistic regression analysis showed that the surgical duration>4 h[OR=2.481,95%CI(1.126,5.466),P=0.024],irrational selection of preventive medication[OR=6.220,95%CI(1.231,31.423),P=0.027]and indwelling drainage tube[OR=2.634,95%CI(1.196,5.802),P=0.016]were the independent risk factors for infection after meningioma resection.Conclusion Clinical pharmacists should strengthen the education on the rational use of preventive medication for physicians,and provide individualized pharmaceutical care and medication monitoring for patients with surgical duration>4 h and indwelling drainage tube.
meningioma resectionpostoperative infectionrisk factorpropensity score matchingrational drug use
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