首页|严重发热伴血小板减少综合征继发肺曲霉感染及吉兰-巴雷综合征个案并文献分析

严重发热伴血小板减少综合征继发肺曲霉感染及吉兰-巴雷综合征个案并文献分析

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目的 提高严重发热伴血小板减少综合征(SFTS)继发肺曲霉感染及吉兰-巴雷综合征(GBS)患者的诊治效果.方法 回顾性分析安徽省立医院重症监护室(ICU)收治的 1 例SFTS继发肺曲霉感染及GBS患者的临床资料,并结合文献对治疗方案进行分析.结果 经多学科联合会诊(MDT)团队诊断结合文献分析发现,SFTS继发肺曲霉感染的同时可能会诱发GBS,三病分别以利巴韦林联合血浆置换、艾沙康唑、人免疫球蛋白联合激素冲击治疗处理.治疗后患者病情逐渐改善,转至外院继续康复治疗.结论 当SFTS患者出现感觉异常或减退、肢体活动障碍等神经系统异常表现时,需警惕GBS,应及早诊治,以降低患者的死亡率,改善预后.
Pulmonary Aspergillosis and Guillain-Barré Syndrome Secondary to Severe Fever with Thrombocytopenia Syndrome:A Case Report and Literature Analysis
Objective To promote the diagnosis and treatment of pulmonary aspergillosis and Guillain-Barré syndrome(GBS)secondary to severe fever with thrombocytopenia syndrome(SFTS).Methods The clinical data of a patient with pulmonary aspergillosis and GBS secondary to SFTS admitted to the intensive care unit(ICU)of Anhui Provincial Hospital were retrospectively collected,and the treatment regimen was analyzed based on relevant literature.Results Based on the multi-disciplinary treatment(MDT)and literature analysis,it was found that SFTS might induce GBS when the patient suffered pulmonary aspergillosis secondary to SFTS.SFTS,pulmonary aspergillosis and GBS were treated with ribavirin combined with plasma exchange,isavuconazole,human immunoglobulin combined with hormone pulse therapy respectively.After treatment,the patient's condition gradually improved,and he was transferred to another hospital for further rehabilitation treatment.Conclusion When the SFTS patients exhibit neurological abnormalities such as sensory abnormalities or decline,limb movement disorders,etc.,GBS needs to be paid attention to and treated early to decrease the patients'mortality and improve the prognosis.

severe fever with thrombocytopenia syndromepulmonary aspergillosisGuillain-Barré syndromepharmaceutical careliterature analysis

谢晓婷、周冉

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安徽省阜阳市太和县人民医院,安徽 阜阳 236000

中国科学技术大学附属第一医院·安徽省立医院,安徽 合肥 230001

严重发热伴血小板减少综合征 肺曲霉感染 吉兰-巴雷综合征 药学监护 文献分析

安徽省高等学校省级质量工程项目

2021jyxm1798

2024

中国药业
重庆市食品药品监督管理局

中国药业

CSTPCD
影响因子:1.369
ISSN:1006-4931
年,卷(期):2024.33(16)
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