Pulmonary Aspergillosis and Guillain-Barré Syndrome Secondary to Severe Fever with Thrombocytopenia Syndrome:A Case Report and Literature Analysis
Objective To promote the diagnosis and treatment of pulmonary aspergillosis and Guillain-Barré syndrome(GBS)secondary to severe fever with thrombocytopenia syndrome(SFTS).Methods The clinical data of a patient with pulmonary aspergillosis and GBS secondary to SFTS admitted to the intensive care unit(ICU)of Anhui Provincial Hospital were retrospectively collected,and the treatment regimen was analyzed based on relevant literature.Results Based on the multi-disciplinary treatment(MDT)and literature analysis,it was found that SFTS might induce GBS when the patient suffered pulmonary aspergillosis secondary to SFTS.SFTS,pulmonary aspergillosis and GBS were treated with ribavirin combined with plasma exchange,isavuconazole,human immunoglobulin combined with hormone pulse therapy respectively.After treatment,the patient's condition gradually improved,and he was transferred to another hospital for further rehabilitation treatment.Conclusion When the SFTS patients exhibit neurological abnormalities such as sensory abnormalities or decline,limb movement disorders,etc.,GBS needs to be paid attention to and treated early to decrease the patients'mortality and improve the prognosis.
severe fever with thrombocytopenia syndromepulmonary aspergillosisGuillain-Barré syndromepharmaceutical careliterature analysis