首页|1例复方聚乙二醇电解质散(Ⅰ)致心律失常病例分析

1例复方聚乙二醇电解质散(Ⅰ)致心律失常病例分析

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目的 为临床安全应用复方聚乙二醇电解质散(Ⅰ)提供参考。方法 通过分析1例胃肠道功能紊乱患者结肠镜检查前使用复方聚乙二醇电解质散(Ⅰ)清肠后出现心悸不适、心律失常药品不良反应(ADR)的病例,结合文献及复方聚乙二醇电解质散(Ⅰ)ADR监测数据,根据《个例药品不良反应收集和报告指导原则》评价其关联性。结果与结论 60岁以上患者和电解质紊乱患者使用复方聚乙二醇电解质散(Ⅰ)存在一定风险。临床使用时应密切关注患者因腹泻、呕吐等原因导致的严重电解质紊乱,一旦发现应立即予相应干预措施,以免诱发心律失常。
Arrhythmia Induced by Compound Polyethylene Glycol Electrolyte Powder(Ⅰ):A Case Analysis
Objective To provide a reference for the safe use of Compound Polyethylene Glycol Electrolyte Powder(Ⅰ)in the clinic.Methods By analyzing a case of patient with gastrointestinal dysfunction who had adverse drug reaction(ADR)of palpitations,discomfort,and arrhythmia after using Compound Polyethylene Glycol Electrolyte Powder(Ⅰ)for bowel cleansing before colonoscopy,based on the related literature and ADR monitoring data of Compound Polyethylene Glycol Electrolyte Powder(Ⅰ),the association between ADRs and drugs was evaluated according to the Guiding Principles for Collection and Reporting of Adverse DrugReactions to Individual Medicinal Products.Result and Conclusion The use of Compound Polyethylene Glycol Electrolyte Powder(Ⅰ)in patients over 60 years old and patients with electrolyte disorder has a certain risk.Clinical use should closely monitor patients with electrolyte disorder induced by diarrhea,vomiting,and other reasons.Once the above symptoms occur,corresponding intervention measures should be taken immediately to avoid inducing arrhythmia.

Compound Polyethylene Glycol Electrolyte Powder(Ⅰ)adverse drug reactionsarrhythmia

奚军伟、孙辉、戴洁、侯少平、王维

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陕西省药品不良反应监测中心,陕西 西安 710065

陕西国际商贸学院,陕西 咸阳 712046

陕西省药品和疫苗检查中心,陕西 西安 710065

复方聚乙二醇电解质散(Ⅰ) 药品不良反应 心律失常

2024

中国药业
重庆市食品药品监督管理局

中国药业

CSTPCD
影响因子:1.369
ISSN:1006-4931
年,卷(期):2024.33(17)