Efficacy of Inhaled Formulations in Patients with Chronic Obstructive Pulmonary Disease Based on Cough and Wheeze Pharmaceutical Care Clinic
Objective To investigate the efficacy of inhaled formulations in patients with chronic obstructive pulmonary disease(COPD)based on the cough and wheeze pharmaceutical care clinic(CWPC).Methods The basic information of 130 patients with COPD admitted to the CWPC of a hospital from October 2021 to June 2023 was collected,and the self-control method was used to compare the clinical outcomes[correct operation rate of inhalation devices,medication adherence score,modified British Medical Research Council(mMRC)score,COPD Assessment Test(CAT)score,frequency of acute exacerbations within one year,incidence of adverse reactions]and the humanistic outcomes[European Quality of Life-Five Dimension-Five Level(EQ-5D-5L)Scale score,patients´ satisfaction level]before the intervention(initial diagnosis)and after intervention(continuous intervention for one year)of CWPC.Results After the intervention,the patients´ correct operation rate of the inhalation devices increased from 36.11%to 83.33%,the medication adherence score increased from 4.50 points to 6.50 points,the mMRC score decreased from 2.00 points to 1.00 point,the CAT score decreased from 21.00 points to 12.00 points,the incidence of adverse reactions decreased from 29.23%to 16.92%,the frequency of acute exacerbations within one year decreased from 2.00 times to 1.00 time,the EQ-5D-5L Scale score increased from 62.00 points to 70.00 points,the patients´ satisfaction level increased from 6.00 points to 12.00 points,and the above indexes were significantly different from those before intervention(P<0.05).Conclusion Clinical pharmacists can significantly improve the efficacy of inhaled formulations for COPD through the CWPC.
cough and wheeze pharmaceutical care clinicpharmaceutical carechronic obstructive pulmonary diseaseinhaled formulationsclinical outcomehumanistic outcome
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维普
