Clinical Evaluation of Dexmedetomidine Combined with Ropivacaine for Ultrasound-Guide Quadratus Lumborum Block in Pediatric Laparoscopic Pyeloplasty
Objective To investigate the clinical efficacy of dexmedetomidine combined with ropivacaine for ultrasound-guided quadratus lumborum block(QLB)in pediatric laparoscopic pyeloplasty.Methods A total of 74 children who underwent laparoscopic pyeloplasty in the hospital from June 2022 to June 2023 were selected and randomly divided into the observation group and the control group by the random number table method,with 37 cases in each group.The children in the two groups underwent ultrasound-guided QLB and received intravenous injection of 0.4 mL/kg of 0.25%Ropivacaine Hydrochloride Injection,on this basis,the children in the observation group received intravenous injection of 1 μg/kg of Dexmedetomidine Hydrochloride Injection.Results Compared with those in the control group,the heart rate(HR)and mean arterial pressure(MAP)at 30 min after pneumoperitoneum,60 min after pneumoperitoneum,and after surgery in the observation group significantly decreased;the FLACC pain assessment scale scores significantly decreased,the Ramsay sedation scale scores were significantly better at 6,12,24,48 h after surgery;the time of the first postoperative remedial analgesia significantly delayed,and the cases of remedial analgesia within 48 h significantly decreased(P<0.05).Both groups did not experience hypotension and bradycardia,but the total incidence of drowsiness,agitation,nausea and vomiting in the observation group was significantly lower than that in the control group(10.81%vs.43.24%,P<0.05).Conclusion Dexmedetomidine combined with ropivacaine for ultrasound-guided QLB in pediatric laparoscopic pyeloplasty is beneficial for maintaining hemodynamic stability,and it can optimize postoperative analgesic and sedative effects,decrease the additional use of analgesics.
万方数据
维普
