Objective To formulate the evaluation criteria for the treatment regimens of chronic kidney disease-mineral and bone disorder(CKD-MBD).Methods The evaluation criteria for CKD-MBD treatment regimens were formulated based on domestic and international CKD-MBD guidelines,literature and drug instructions.The treatment regimens of 512 patients with CKD-MBD in CKD3a-5D phase admitted to the hospital in 2020 were retrospectively evaluated and analyzed.Results The formulated CKD-MBD treatment regimens were aimed at adjusting the serum corrected calcium,serum phosphorus and intact parathyroid hormone levels,and the criteria mainly involved the rationality evaluation of the use of phosphate binders and active vitamin D.The irrational rate of treatment regimens in 512 patients with CKD-MBD was 26.95%,among which the irrational rate of using phosphate binders(Calcium Acetate Tablets,Sevelamer Carbonate Tablets,Lanthanum Carbonate Chewable Tablets,Calcium Carbonate and Vitamin D3 Tablets)was 16.80%,and that of using active vitamin D(Calcitriol Soft Capsules)was 11.52%.Conclusion The formulated evaluation criteria for CKD-MBD treatment regimens are targeted,convenient and practical,which can be used to standardize CKD-MBD treatment regimens and promote rational clinical drug use.
关键词
慢性肾脏病矿物质与骨异常/药物治疗方案/评价标准/合理用药
Key words
chronic kidney disease-mineral and bone disorder/drug treatment regimen/evaluation criteria/rational drug use
维普
万方数据