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上海市某医养结合养老机构老年患者用药现状调查

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目的 提升老年患者合理用药水平。方法 收集上海市某医养结合养老机构2023年9月至12月在住老年患者的健康档案,统计其一般资料、疾病情况及用药情况,采用Morisky用药依从性量表评估用药依从性,采用美国老年医学会2023年更新版老年人潜在不适当用药(PIM)的Beers标准筛查PIM。结果 共纳入患者1 566例,平均年龄(81。25±7。04)岁,平均患慢性疾病(3。14±1。49)种,平均每日因慢性疾病用药(5。58±3。92)种,多重用药(≥5种)发生率为59。32%。Morisky服药依从性量表评分平均(6。08±1。67)分,其中依从性高、中、低的分别有193例(12。32%)、751例(47。96%)、622例(39。72%)。942例患者(60。15%)存在至少1项PIM,共检出PIM 2 891例次;包括老年人应避免的PIM 1 892例次,药物-疾病/药物-综合征相互作用导致的PIM 540例次,老年人应谨慎使用的药物378例次,老年人应避免的潜在药物相互作用的PIM 81例次。结论 医养结合养老机构老年患者共病、多重用药问题突出,服药依从性较低,且PIM情况较严重。临床药师应全面评估老年患者用药情况,并提供合理化建议;老年多学科团队应加强对老年患者用药风险的识别与关注,强化用药安全管理。
Investigation on the Medication Use Among Elderly Patients in an Old-Age Care Institution of Medical-Nursing Combined in Shanghai
Objective To promote the rational drug use in elderly patients.Methods The health records of elderly patients residing in an old-age care institution of medical-nursing combined in Shanghai from September to December 2023 were collected,the patients'general data,disease and medication use information was recorded.The medication adherence was evaluated by the Morisky Medication Adherence Scale,the potentially inappropriate medications(PIMs)in the elderly were screened based on the American Geriatrics Society 2023 updated AGS Beers Criteria® for potentially inappropriate medication use in older adults.Results A total of 1 566 patients were included,with an average age of(81.25±7.04)years,an average of(3.14±1.49)chronic diseases,and an average of(5.58±3.92)medications taken daily for chronic diseases;the incidence of polypharmacy(≥ five types)was 59.32%.The average score of Morisky Medication Adherence Scale was(6.08±1.67)points,among which 193(12.32%),751(47.96%),622 cases(39.72%)had high,medium and low adherence,respectively.At least one PIMs were detected in 942 patients(60.15%),and 2 891 case times of PIMs were detected,including 1 892 case times of PIMs that the elderly should avoid,540 case times of PIMs induced by drug-disease/drug-syndrome interactions,378 case times of PIMs induced by medications that the elderly should use with caution,and 81 case times of PIMs induced by potentially drug interactions that the elderly should avoid.Conclusion Elderly patients in the old-age care institution of medical-nursing combined have prominent comorbidities and polypharmacy problems,low medication adherence,and severe PIMs.Clinical pharmacists should comprehensively evaluate the medication use of elderly patients and provide rational recommendations;multidisciplinary teams for the elderly should strengthen the identification and attention to medication risks for elderly patients,and enhance medication safety management.

old-age care institution of medical-nursing combinedrisk of drug usepotentially inappropriate medication

刘夏、杨秋娅、张金明、李升华

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上海泰康申园康复医院,上海 200032

医养结合养老机构 用药风险 潜在不适当用药

2024

中国药业
重庆市食品药品监督管理局

中国药业

CSTPCD
影响因子:1.369
ISSN:1006-4931
年,卷(期):2024.33(24)