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中药治疗急性冠状动脉综合征研究进展

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目的 总结急性冠状动脉综合征(ACS)的证型与中药治疗方案。方法 检索知网、万方、维普、PubMed等数据库自建库起至2023年12月31日中药治疗各种证型ACS的相关文献,总结中药在ACS治疗中的应用现状,并提出建议。结果与结论 中药用于ACS当前以防治为主要目的,以气为本,以调和阴阳为治疗原则,通过多靶点、多环节干预稳定斑块,并发展出中成药制剂,应用更便利。组方多具有保护血管内皮、抑制平滑肌细胞增生与迁移、减缓脂质体过氧化、调节脂代谢与抑制血小板聚集等作用,对防治动脉粥样硬化有重要意义。未来将现代制药工艺应用于相关中药制剂开发,通过创新剂型,联合其他中医治疗手段等,有望取得更好的疗效。
Resarch Progress of Traditional Chinese Medicine in the Treatment of Acute Coronary Syndrome
Objective To summarize the syndrome types and traditional Chinese medicine(TCM)treatment regimens of acute coronary syndrome(ACS).Methods Relevant literature on TCM in the treatment of various syndrome types of ACS in the databases such as CNKI,WanFang,VIP,and PubMed from the inception of each database to December 31,2023 was searched.The current application of TCM in the treatment of ACS was summarized,and the recommendations were provided.Results and Conclusion At present,TCM treatment for ACS focuses on prevention and treatment based on Qi and regulation of Yin and Yang,and the plaques are stabilized by multi-target and multi-link intervention;Chinese patent medicines have been developed,which are more convenient in application.Most of the prescriptions have the functions of protecting vascular endothelium,inhibiting proliferation and migration of smooth muscle cells,slowing down liposome peroxidation,regulating lipid metabolism and inhibiting platelet aggregation,which are of great significance in the prevention and treatment of atherosclerosis.In the future,applying modern pharmaceutical technology to the development of related TCM preparations is expected to achieve better efficacy by innovative dosage forms and combined with other TCM treatment methods.

acute coronary syndromedialecticaltraditional Chinese medicineresearch progress

张冠雄、耿晓娟、田露、潘桂赟、王作顺

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天津中医药大学研究生院,天津 301636

天津中医药大学文化与健康传播学院,天津 301636

天津中医药大学中医学院,天津 301636

天津市中医药研究院附属医院,天津 300120

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急性冠状动脉综合征 辨证 中药 研究进展

2024

中国药业
重庆市食品药品监督管理局

中国药业

CSTPCD
影响因子:1.369
ISSN:1006-4931
年,卷(期):2024.33(24)