Analysis of Pus Pathogenic Bacteria Culture and Drug Susceptibility in Patients with Anal Fistula Complicated with Infection in Our Hospital
Objective:To investigate the culture and drug susceptibility results of pus pathogenic bacteria in patients with anal fistula complicated by infection in our hospital,to provide a theoretical reference for the clinical rational use of anal fistula.Methods:The clinical data of 174 patients with anal fistula complicated with infection admitted in our hospital from May 2019 to May 2021 were retrospectively analyzed.The pus samples of all patients were collected for pathogenic bacteria culture,and the distribution of pathogenic bacteria and the drug susceptibility results of main pathogenic bacteria were analyzed.Results:A total of 234 pathogenic bacteria strains were detected in 174 patients with anal fistula complicated with infection,including 40 gram-positive bacteria(17.09％)and 194 gram-negative bacteria(82.91％).Gram-positive bacteria were dominated by Staphylococcus aureus(20 strains,accounting for 8.56％),gram-negative bacte-ria were dominated by Escherichia coli(118 strains,accounting for 50.43％),followed by Klebsiellapneumoniae(22 strains,accounting for 9.41％).The drug susceptibility results showed that Staphylococcus aureus was extremely sensitive to piperacillin,vancomycin,and linezolid(the sensitivity rate was all 100％),while it was relatively resistant to penicillin,erythromycin,and rifampicin(resistant to drug rates were＞80％).Escherichia coli showed resistance to most antibacterial drugs,and only showed extreme sensitivity to amikacin,imipenem and meropenem(the sensitivity rate was all 100％).Klebsiellapneumoniae also showed resistance to most antibacterial drugs,and only showed extreme sensitivity to ceftazidime,penicillin,aztreonam,imipenem,and meropenem(the sensitivity rate was all 100％).Conclusion:The pathogenic bacteria in the pus of patients with anal fistula complicated with infection were mainly gram-negative bacte-ria.The top three pathogenic bacteria in the detection rate were Escherichia coli,Klebsiellapneumoniae and Staphylococcus aureus.There are a variety of antibiotics with high sensitivity,but most of them are special antibiotics.In clinical treatment,anti-gram-negative bacteria drugs should be mainly used,and rational use of drugs should be combined with the results of pathogenic bacteria culture and drug suscep-tibility to improve the therapeutic effect.
NETL
NSTL
万方数据
维普
