Arthritis is a chronic inflammatory disease that occurs in the joints and surrounding tissues,and is a common disease that seriously affects the quality of life of patients.At present,the treatment of arthritis is mainly through drug,physica land surgical thearpy to relieve the symptoms of patients and improve the joint function of patients.The main drugs for the treatment of arthritis are non-steroidal anti-inflammatory drugs,but such drugs have certain adverse reactions,affecting long-term use.Curcumin has hypolipidemic,anti-inflammatory,antioxidant,analgesic,antitumor effects,and a large number of pharmacological studies have shown that curcumin has great potential in the treatment of arthritis.However,curcumin has the disadvantages of poor aqueous solubility,poor stability and low bioavailability,which seriously limit its therapeutic efficacy and clinical application in the treatment of arthritis.Studies have shown that nanoformulations can effectively solve the above problems and greatly improve the efficacy of curcumin.In this study,the latest research progress on curcumin and curcumin nanopreparations in the treatment of arthritis was reviewed in terms of the mechanism of action and clinical application of curcumin in the treatment of arthritis,curcumin nanopreparation in the treatment of arthritis,with the aim to providing a references for the treatment of arthritis with curcumin and its nanopreparations,as well as for the further development of other traditional Chinese medicinal herbs.
维普
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