Research Progress on Extraction and Purification Process of Active Ingredients from Phyllanthus Urinaria Land Quality Control
The main components of phyllanthus urinaria L include flavonoids,phenolic acids,lignans,alkaloids and polysaccha-rides,etc.It has the functions of clearing away heat and toxic materials,relieving water and swelling,eliminating accumulation in the eyes,and resisting bacteria,oxidation and virus,anti-thrombus,improve the activity of spleen cells,and long-term use of the character-istics of less toxic side effects.Clinically,phyllanthus urinaria L combined with other drugs in the treatment of hepatitis B,fatty liver,the effect is good.Because of its definite effect and good prospect of development and utilization,the research and technology of extrac-tion,utilization and quality control of various components in phyllanthus urinaria L.keep innovating.In order to provide the reference for the development and utilization of phyllanthus urinaria L,the research on the purification technology of some active components and quality control in recent 10 years of phyllanthus urinaria L.was reviewed.It was found that:①for the extraction of total phenols in phyl-lanthus urinaria L,the ultrasonic method was suitable for industrial production,and the membrane filtration and column chromatography were the most promising technologies for the extraction of corilagin.At present,the extraction technology of other components is mainly based on the traditional method,and the new method is in the experimental exploration stage.②Although there are many studies on the pharmacological effects of phyllanthus urinaria L,the structure-activity relationship of single active component is less,which is not con-ducive to further development of new drugs.③The quality control of phyllanthus urinaria L mainly concentrated on the content determina-tion and fingerprint,but there was no report on the research of heavy metals and 33 heavy pesticide residues.There are still some easily confused products in the market,such as bitter Phyllanthus,pearl grass,etc.,At present,there is still a lack of simple and effective means of identification.
NETL
NSTL
万方数据
