In recent years,biofilm,as a natural biomaterial,has gained significant attention in the field of nano-drug delivery.Its unique biocompatibility and controllability make it a promising tool for enhancing drug targeting and reducing immune responses.This paper provides a comprehensive review of the use of biofilm in nano-drug delivery,covering various types of biofilms such as erythrocyte membrane,leukocyte membrane,platelet membrane,macrophage membrane,and bacterial membrane.We also discuss its potential applications in tumor treatment,immunomodulation,and infection control,as well as future research directions and potential prospects for its utilization.
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