Objective To analyze the risk of acute coronary events in patients with type 2 diabetes mellitus,and to pro-vide basis for the management of patients.Methods Based on the data of Wenzhou chronic disease collaborative management system,a retrospective cohort study was conducted.A total of 277 205 newly diagnosed type 2 diabetes mellitus patients from 2010 to 2020 were included in the analysis.The incidence and death information were obtained by matching the ID number with the data of acute coronary events and deaths.COX regression model was used to analyze the relationship between the complica-tions of diabetes patients at the time of diagnosis and the risk of acute coronary events.Results During the follow-up period,acute coronary events occurred in 3 241 cases,and the incidence rate of coronary heart disease was 1 169.17/100 000;1 083 di-abetes patients died from coronary heart disease,with a fatality rate of 390.69/100 000.Taking the patients diagnosed without complications as the reference,the HR of acute coronary disease in patients with one complication and two or more was 1.382(95％CI:1.266-1.508)and 1.661(95％CI:1.221-2.259)respectively.Conclusion Type 2 diabetes patients have a high risk of morbidity and mortality from acute coronary events,so intervention should be strengthened in patient management to ac-tively prevent and treat complications.
type 2 diabetes mellitusacute coronary eventcohort study
NETL
NSTL
维普
万方数据
