Objective To construct a scientific and reasonable operation efficiency evaluation system of hospital clinical departments,so as to provide decision-making basis for hospital development.Methods Based on the medical data of 51 inpa-tient departments from January to December 2023,6 evaluation indicators were selected from the three dimensions of workload,work efficiency and income structure,and the TOPSIS method was applied to evaluate the operational efficiency.Results The departments of spinal surgery,ophthalmology and the first ward of gastrointestinal surgery had high scores and were the superior departments of the hospital,with the comprehensive score index 0.709,0.706 and 0.705 respectively.The departments of bone oncology,oral and maxillofacial surgery,medical cosmetic and burn plastic surgery had lower scores and were the inferior depart-ments,with he comprehensive score 0.133,0.127 and 0.106 respectively.Conclusion The use of expert scoring method and TOPSIS method for inpatient department performance evaluation resulted in findings that matched the actual situation.The indica-tor system can be combined with hospital performance appraisal to provide performance incentives for strong departments and pro-vide development basis for weak departments.