Research progress of heat-clearing and blood-cooling prescriptions in the treatment of psoriasis
Psoriasis,which can involve the skin,nails and joints,is a chronic,painful,disfiguring and disabling noncommunicable disease for which there is no cure,affecting more than 60 million adults and children around the world.At present,the pathogenesis is not clear,bringing enormous physical and mental burden to patients.Traditional Chinese medicine believes that blood-heat syndrome is the most common in psoriasis,and clinical studies have confirmed the effectiveness and safety of heat-clearing and blood-cooling prescriptions in the treatment of psoriasis with blood-heat syndrome.Mechanism studies have also confirmed that heat-clearing and blood-cooling prescriptions can affect the proliferation and differentiation of HaCaT cells,immune function of CD+4T lymphocytes,inflammatory reaction and vascular hyperplasia through multiple pathways and targets in the treatment of psoriasis.This paper systematically reviewed the research progress and achievements of heat-clearing and blood-cooling prescriptions in the treatment of psoriasis,in order to provide support for the clinical treatment and research of psoriasis with traditional Chinese medicine.
Heat-clearing and blood-coolingTraditional Chinese medicineBlood-heatPsoriasisMechanismResearch progress