首页|茯山藤米茶预防结直肠腺瘤内镜下切除后复发的临床疗效观察

茯山藤米茶预防结直肠腺瘤内镜下切除后复发的临床疗效观察

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目的:观察茯山藤米茶预防结直肠腺瘤(CRA)术后复发的临床疗效及安全性.方法:收集于中国中医科学院广安门医院内镜中心行CRA切除的患者124例,随机分为治疗组和对照组,各62例.入组患者均接受生活饮食指导,治疗组配合茯山藤米茶内服,治疗12个月,比较两组患者CRA的复发率、中医证候积分变化、便质改变情况及安全性指标,并分析腺瘤复发的危险因素.结果:治疗组年复发率为33.93%(19/56)显著低于对照组的61.82%(34/55)(P<0.01).治疗组较对照组口臭、神疲乏力、气短胸闷、畏寒肢冷及失眠等其他症状积分及大便偏稀情况改善显著(P<0.05).性别、年龄、BMI、腺瘤数量及大小均为腺瘤复发的危险因素.两组患者治疗前后安全性指标均未见异常.结论:茯山藤米茶可显著降低CRA患者术后1年复发率,改善患者临床症状,安全性高.
Clinical observation of Fushan Tengmi Tea in preventing recurrence of colorectal adenoma after endoscopic resection
Objective:To observe the clinical efficacy and safety of Fushan Tengmi Tea in preventing recurrence of colorectal adenoma(CRA)after surgery.Methods:A total of 124 patients who underwent CRA resection at the Endoscopy Center of Guang'anmen Hospital,China Academy of Chinese Medical Sciences were randomly divided into treatment group and control group,with 62 cases in each group.The patients in the group received dietary guidance,and the treatment group was treated with Fushan Tengmi Tea for 12 months,and the recurrence rate,traditional Chinese medicine syndrome score change,changes of stool characteristics and safety index of CRA were compared between the two groups,and the risk factors for adenoma recurrence were analyzed.Results:The annual recurrence rate of the treatment group was 33.93%(19/56),which was significantly lower than that of the control group 61.82%(34/55)(P<0.01).Compared with the control group,scores of other symptoms such as halitosis,mental fatigue,shortness of breath and chest tightness,chills and cold limbs,insomnia and loose stool were significantly improved in the treatment group(P<0.05).Sex,age,BMI,number and size of adenomas were all risk factors for adenoma recurrence.There were no abnormalities in the safety indexes of the patients before and after treatment in the two groups.Conclusion:Fushan Tengmi Tea can significantly reduce the recurrence rate of patients after CRA at one year,improve the clinical symptoms of patients,and have high safety.

Colorectal adenomaRecurrence rateFushan Tengmi TeaTraditional Chinese medicineClinical efficacy

诸葛丽、郭哲宇、王柏庆、周斌

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中国中医科学院广安门医院,北京 100053

北京市石景山区中医医院内科,北京 100043

结直肠腺瘤 复发率 茯山藤米茶 中医药 临床疗效

首都临床特色应用研究项目

Z181100001718049

2024

中华中医药杂志
中华中医药学会

中华中医药杂志

CSTPCD北大核心
影响因子:1.135
ISSN:1673-1727
年,卷(期):2024.39(1)
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