摘要
目的:观察中药联合营养膳食疗法治疗小儿厌食症的临床疗效.方法:138例厌食症(脾胃气虚证)患儿随机分为3组,中药、西药对照组除均予一般饮食宣教外,西药对照组口服五维赖氨酸颗粒,中药对照组口服运脾喜食汤;联合治疗组口服运脾喜食汤,并予营养膳食疗法,疗程均为4周.比较治疗后各临床症状、体征及营养指标的改善情况.结果:治疗后,联合治疗组、中药对照组、西药对照组总有效率分别为91.07％(51/56)、75.00％(39/52)、36.67％(11/30)(P＜0.01);联合治疗组的总有效率及食欲食量、腹痛、嗳气呕吐、便秘、汗出、面色、皮肤、舌脉等中医证候积分疗效,蛋白质、体脂肪、肌肉量、TRF、RBP、PA、HgB、MCH、二羟基维生素D等营养指标疗效均优于中、西药对照组(P＜0.01);联合治疗组的食量、面色中医证候积分疗效优于中药对照组(P＜0.05);中药对照组的综合疗效,食欲、食量、腹痛、嗳气呕吐、便秘、皮肤、舌脉中医证候积分疗效,蛋白质、体脂肪、肌肉量、TRF、RBP、PA、HgB、MCH、二羟基维生素D等营养指标疗效均优于西药对照组(P＜0.05).结论:中药联合营养膳食疗法治疗小儿厌食症(脾胃气虚证)具有优势,营养膳食疗法对中药有增效作用,值得深入研究.
Abstract
Objective:To observe the clinical effect of traditional Chinese medicine combined with nutritional diet in the treatment of infantile anorexia.Methods:A total of 138 children with anorexia(spleen and stomach qi deficiency syndrome)were randomly divided into combined treatment group,traditional Chinese medicine control group and Western medicine control group.In addition to general diet education,the western medicine control group took orally five dimensional lysine granules and the Chinese medicine control group took orally Chinese medicine;The combined treatment group was treated with oral Chinese medicine and nutritional diet.All courses of treatment were given for 4 weeks.After treatment,the improvement of various clinical symptoms,signs and nutritional indicators were compared.Results:After treatment,the total response rate of the combined treatment group,TCM control group and western medicine control group was 91.07％(51/56),75.00％(39/52),and 36.67％(11/30)(P＜0.01).The total response rate,the efficacy of food intake,abdominal pain,belching,vomiting,constipation,sweating,complexion,skin,tongue image,protein,body fat,muscle mass,TRF,RBP,PA,HgB,MCH,dihydroxyvitamin D and other nutritional indicators were all better than those of the Chinese medicine and western medicine control group(P＜0.01).In the combined treatment group,the integral effect of food intake and complexion was better than that of the TCM control group(P＜0.05).In the TCM control group,the comprehensive efficacy,appetite,food intake,abdominal pain,belching,vomiting,constipation,skin,tongue vein,protein,body fat,muscle mass,TRF,RBP,PA,HgB,MCH,and dihydroxyvitamin D were all better than those of the western medicine control group(P＜0.05).Conclusion:Traditional Chinese medicine combined with nutritional diet therapy has advantages in the treatment of infantile anorexia(spleen and stomach qi deficiency syndrome).Nutritional diet therapy has synergistic effect on traditional Chinese medicine,which is worthy of further study.
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