Pathogenesis and treatment of cerebral small vessel disease of qi deficiency and blood stasis syndrome based on the theory of qi-yang nurturing and inspiring
Cerebral small vascular disease(CSVD)is a series of common clinical syndromes involving intracranial small/micro arteries,capillaries,small/micro veins,etc.,with stroke(deep small infarction,cerebral hemorrhage),cognitive function decline and emotional disorders as the main clinical manifestations.Focusing on the key factors of senile diseases and encephalopathy,professor GE Jinwen put forward the theory of qi-yang nurturing and inspiring.According to the theory,the deficiency of qi-yang leads to the inability of qi-yang to warm or promote,then the loss of the spirit in brain,and the disorder of the mechanism,including five viscera and six organs,four limbs and skeletons,qi-blood essence-fluid,and meridian and blood vessels,which both above eventually results in disorders of emotion,memory and cognition,and abnormalities of physical function.Insufficient qi and yang,blood stasis is the core pathogenesis of CSVD.In this paper,based on the pathogenesis of CSVD and the guidance of the theory of qi-yang nurturing and inspiring theory,the pathogenesis evolution of CSVD qi-deficiency and blood-stasis syndrome is proposed,including qi-yang deficiency,yin and fluid deficiency,qi stagnation and blood stasis,endogenous phlegm and dampness,and lack of nourishment of mind,and so on.In addition,the main treatment methods should be to benefit qi(yang)and promote blood circulation,and flexibly combining with other medicines,such as invigorating qi(yang)and nourishing yin,regulating qi mechanism,supplementing qi,warming yang and solidification,eliminating phlegm and dampness,promoting blood circulation and removing blood stasis,nourishing soul and calming the spirit,etc..The paper intends to provide different perspectives for the diagnosis and treatment of traditional Chinese medicine clinical syndrome differentiation.
Cerebral small vascular disease(CSVD)Theory of qi yang nurturing and inspiringQi deficiency and blood stasis syndromePathogenesisTreatment principles and methods