摘要
目的:观察2型糖尿病(T2DM)合并下肢动脉粥样硬化性病变(LEAD)的中医体质类型及分析各体质与相关指标是否存在相关性,进而为T2DM合并LEAD的切实可行防治提供有意义的理论指导依据.方法:以103例T2DM合并LEAD患者为调查对象.将所调查的T2DM合并LEAD分为平和、气虚、阴虚、阳虚、痰湿、湿热、血瘀、气郁、特禀体质,再将体质数据与所收集患者的相关指标整合,利用SPSS 25.0软件进行统计学分析.结果:103例T2DM合并LEAD患者的主要体质中绝大部分为偏颇体质(87例),小部分为平和质(16例).T2DM合并LEAD患者不同体质之间,年龄、身体质量指数(BMI)、腰围(WC)、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、空腹血糖(FPG)、糖化血红蛋白(HbA1c)差异有统计学意义(P＜0.01).结论:T2DM合并LEAD患者的中医体质主要为阳虚质、痰湿质、平和质、血瘀质4种体质.T2DM合并LEAD阳虚质、气虚质患者年龄较大;痰湿质、湿热质患者BMI较高;痰湿质患者WC较高;痰湿质患者TG、TC较高,血瘀质患者HDL较低,痰湿质、湿热质患者LDL较高;阴虚质患者FPG较高;气虚质患者HbA1c较高.
Abstract
Objective:To observe the type of traditional Chinese medicine constitution of type 2 diabetes mellitus(T2DM)complicated with lower extremity atherosclerotic disease(LEAD)and analyze whether there is correlation between different constitution and indicators,so as to provide meaningful theoretical guidance for the practical prevention and treatment of T2DM complicated with LEAD.Methods:A total of 103 T2DM patients with LEAD were investigated.The investigated T2DM patients with LEAD were divided into nine constitutions:calm,qi deficiency,yin deficiency,yang deficiency,phlegm-dampness,damp-heat,blood stasis,qi-stagnation and characteristic constitution.Then,the constitution data and related indicators of patients were integrated into Excel and analyzed by SPSS 25.0 statistical software.Results:Most of the main constitutions of T2DM patients with LEAD were biased constitutions(87 patients),and a small part were peaceful constitutions(16 patients).There were statistical differences in age,BMI,WC,TG,TC,HDL,LDL,FPG and HbA1c among different TCM constitutions in T2DM patients with LEAD(P＜0.01).Conclusion:The main constitutions of TCM in T2DM patients with LEAD are yang deficiency,phlegm-dampness,peace and blood stasis.The age of T2DM patients with LEAD yang deficiency and qi deficiency is older.Patients with phlegm-dampness and damp-heat have higher BMI,and patients with phlegm-dampness have higher WC;TG and TC are higher in phlegm-dampness patients,HDL is lower in blood-stasis patients,and LDL is higher in phlegm-dampness patients and damp-heat patients.Patients with yin deficiency have higher FPG and patients with qi deficiency have higher HbA1c.
基金项目
辽宁省"兴辽英才计划"青年拔尖人才资助项目(XLYC1807145)
沈阳市科学技术计划项目(18-013-0-82)
辽宁省教育厅科学研究项目(L201711)
NETL
NSTL
万方数据