Correlation study on clinical characteristics and traditional Chinese medicine syndromes of 58 bronchiectasis patients with frequent acute exacerbation
Objective:To analyze the clinical characteristics of bronchiectasis patients with acute exacerbations within one year and the correlation with the distribution of traditional Chinese medicine(TCM)syndromes through cross-sectional investigation.Methods:A total of 120 bronchiectasis patients were selected from the outpatient and ward department of pulmonary disease of Xiyuan Hospital,China Academy of Chinese Medical Sciences from April 2021 to March 2022.The number of acute exacerbations with one year and the patient's bronchiectasis severity index(BSI),respiratory symptom score,modified medical research council(mMRC),pulmonary function,course of bronchiectasis,anxiety and depression scale score,sputum culture,lung CT,etc.were analyzed,and divide the patients into two groups for comparison,in order to explore the distribution of TCM syndrome types.Results:Among the 120 bronchiectasis patients,58(48.33％)were frequent exacerbators and 62(51.67％)were infrequent exacerbators.Spearman correlation analysis showed that the number of acute exacerbations in one year was significantly positively correlated with BSI grading,bronchiectasis course,respiratory symptoms score,anxiety scale score,depression scale score,mMRC and lung CT(P＜0.01,P＜0.05).There was 51 patients[87.93％(51/58)]of excess and deficiency syndromes in frequent exacerbators group,while one patient[1.61％(1/62)]of excess and deficiency syndromes in infrequent exacerbators group.Conclusion:The number of acute exacerbations in patients with bronchiectasis is significantly correlated with their clinical characteristics.With the increase of acute exacerbation times,TCM syndromes show a trend from excess to deficiency,and excess and deficiency syndromes.
BronchiectasisAcute exacerbationClinical characteristicsTraditional Chinese medicine syndrome typesCross-sectional study
NETL
NSTL
万方数据
