洋甘菊抗哮喘活性部位的提取工艺研究
Study on extraction technology of anti-asthma active part of Matricarla chamomilla L.
刘飞 1热依木古丽·阿布都拉 2信学雷 2李茜3
作者信息
- 1. 新疆医科大学附属中医医院,乌鲁木齐 830000
- 2. 中国科学院干旱区植物资源化学重点实验室/新疆特有药用资源利用省部共建国家重点实验室培育基地/中国科学院新疆理化技术研究所,乌鲁木齐 830011
- 3. 新疆医科大学附属中医医院,乌鲁木齐 830000;新疆中药炮制研究重点实验室,乌鲁木齐 830000
- 折叠
摘要
目的:运用正交试验优化洋甘菊抗哮喘活性部位的提取工艺.方法:以洋甘菊特征成分咖啡酰基奎宁酸类(3,4-二-O-咖啡酰基奎宁酸和4,5-二-O-咖啡酰基奎宁酸)化合物的含量、提取率以及提取物抗哮喘体外筛选作为考察指标,对洋甘菊抗哮喘活性成分的提取工艺进行评价.结果:确定最优提取条件为:70％乙醇作为提取溶剂,料液比为1:30,回流提取2次,每次提取时间2 h.结论:运用正交试验确定洋甘菊抗哮喘活性成分的最优提取工艺.
Abstract
Objective:To optimize the extraction process of anti-asthma active parts of chamomile by using single factor orthogonal test.Methods:The single factor orthogonal design was used to evaluate the extraction technology of anti-asthma active components of chamomile,taking the content,extraction rate and in vitro screening of anti-asthma extracts of the characteristic components of chamomile,namely caffeoyl quinic acid(3,4-di-O-caffeoyl quinic acid and 4,5-di-O-caffeoyl quinic acid)as the inspection indexes.Results:The optimal extraction conditions were determined as follows:70％ethanol was used as extraction solvent,the ratio of solid to liquid was 1:30,reflux extraction was carried out twice,and each extraction time was 2 h.Conclusion:The single factor orthogonal experiment is used to determine the optimal extraction process of anti-asthma active components of chamomile.
关键词
洋甘菊/抗哮喘/正交试验/提取工艺Key words
Matricaria chamomilla L./Anti-asthma/Single factor orthogonal test/Extraction technology引用本文复制引用
基金项目
新疆维吾尔自治区自然科学基金(2021D01E32)
乌鲁木齐市科技局优秀青年科技人才培养项目()
出版年
2024
NETL
NSTL
万方数据