首页|洋甘菊抗哮喘活性部位的提取工艺研究

洋甘菊抗哮喘活性部位的提取工艺研究

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目的:运用正交试验优化洋甘菊抗哮喘活性部位的提取工艺.方法:以洋甘菊特征成分咖啡酰基奎宁酸类(3,4-二-O-咖啡酰基奎宁酸和4,5-二-O-咖啡酰基奎宁酸)化合物的含量、提取率以及提取物抗哮喘体外筛选作为考察指标,对洋甘菊抗哮喘活性成分的提取工艺进行评价.结果:确定最优提取条件为:70%乙醇作为提取溶剂,料液比为1:30,回流提取2次,每次提取时间2 h.结论:运用正交试验确定洋甘菊抗哮喘活性成分的最优提取工艺.
Study on extraction technology of anti-asthma active part of Matricarla chamomilla L.
Objective:To optimize the extraction process of anti-asthma active parts of chamomile by using single factor orthogonal test.Methods:The single factor orthogonal design was used to evaluate the extraction technology of anti-asthma active components of chamomile,taking the content,extraction rate and in vitro screening of anti-asthma extracts of the characteristic components of chamomile,namely caffeoyl quinic acid(3,4-di-O-caffeoyl quinic acid and 4,5-di-O-caffeoyl quinic acid)as the inspection indexes.Results:The optimal extraction conditions were determined as follows:70%ethanol was used as extraction solvent,the ratio of solid to liquid was 1:30,reflux extraction was carried out twice,and each extraction time was 2 h.Conclusion:The single factor orthogonal experiment is used to determine the optimal extraction process of anti-asthma active components of chamomile.

Matricaria chamomilla L.Anti-asthmaSingle factor orthogonal testExtraction technology

刘飞、热依木古丽·阿布都拉、信学雷、李茜

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新疆医科大学附属中医医院,乌鲁木齐 830000

中国科学院干旱区植物资源化学重点实验室/新疆特有药用资源利用省部共建国家重点实验室培育基地/中国科学院新疆理化技术研究所,乌鲁木齐 830011

新疆中药炮制研究重点实验室,乌鲁木齐 830000

洋甘菊 抗哮喘 正交试验 提取工艺

新疆维吾尔自治区自然科学基金乌鲁木齐市科技局优秀青年科技人才培养项目

2021D01E32

2024

中华中医药杂志
中华中医药学会

中华中医药杂志

CSTPCD北大核心
影响因子:1.135
ISSN:1673-1727
年,卷(期):2024.39(3)
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