首页|基于3种评分工具的国内中药复方随机对照试验报告质量评价研究

基于3种评分工具的国内中药复方随机对照试验报告质量评价研究

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  • NETL
  • NSTL
  • 万方数据
目的:评价近20年的中药复方随机对照试验(RCT)报告的质量.方法:对中国知网(CNKI)、万方(WangFang COJ)、维普(VIP-CSTJ)、中国生物医学文献数据库(CBM)等中文数据库进行检索,纳入文献采用改良Jadad量表、Cochrane风险偏倚评估工具2.0评价;用CONSORT-CHM formulas进行质量分析.结果:共纳入413篇文献,经改良Jadad量表评价:低质量文献共404篇(97.8％),高质量文献仅9篇(2.2％);经Cochrane风险偏倚评估工具2.0评价:高风险文献有406篇(98.3％),7篇(1.7％)被判定为不确定,无低风险文献;经CONSORT-CHM formulas评价:纳入文献平均得分为28.8分,得分在28.8分以下的文献共255篇(61.7％),得分在28.8分以上共158篇(38.3％).结论:目前国内中药复方RCT报告质量偏低,偏倚风险过大.
Study on evaluating the quality of reports of randomized controlled trials of traditional Chinese medicine compounds in China based on three scoring tools
Objective:To evaluate the quality of Chinese medicine compounds randomized controlled trial(RCT)reports in the past 20 years.Methods:Chinese databases such as China Knowledge Network(CNKI),Wanfang(WangFang COJ),Vipu(VIPCSTJ),and China Biomedical Literature Database(CBM)were searched,the included literature was evaluated by the modified Jadad scale and the Cochrang Risk of Bias Assessment Tool 2.0;quality analyses were performed by CONSORTCHM formulas.Results:A total of 413 papers were included,evaluated by the modified Jadad scale:404 papers(97.8％)with low quality,and only 9 papers(2.2％)with high quality;evaluated by the Cochrane Risk of Bias Assessment Tool 2.0:there were 406 papers(98.3％)at high risk,and 7 papers(1.7％)were judged to be indeterminate,with no low-risk papers;evaluated by the CONRORTCHM formulas:the average score of the included literature was 28.8,with a total of 255(61.7％)literature scoring below 28.8,158(38.3％)scoring above 28.8.Conclusion:At present,the reporting quality of RCT of Chinese medicine compounds in China is low and the risk of bias is too high.

Traditional Chinese medicine compoundsRandomized controlled trial(RCT)CONSORT-CHM formulasModified Jadad scaleCochrane Risk of Bias Assessment Tool 2.0Quality evaluation

李德众、庞立健、王琳琳、王天娇、王梅、王佳然、邹吉宇、于睿智、臧凝子、吕晓东

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辽宁中医药大学,沈阳 110847

辽宁中医药大学附属医院,沈阳 110032

中药复方 随机对照试验 CONSORT-CHM formulas 改良Jadad量表 Cochrane风险偏倚评估工具2.0 质量评价

国家自然科学基金面上项目国家自然科学基金青年科学基金国家自然科学基金青年科学基金吕晓东辽宁省名中医传承工作室建设项目

822744408200429482104804辽中医药函[2021]1号

2024

中华中医药杂志
中华中医药学会

中华中医药杂志

CSTPCD北大核心
影响因子：1.135
ISSN：1673-1727
年,卷(期)：2024.39(4)
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