Effects of chronic disease management pattern based on the method of tonifying kidney and promoting blood circulation in chronic kidney disease patients of stage 3 with kidney deficiency and blood stasis type
Objective:To observe the effect of chronic disease management pattern based on the method of tonifying kidney and promoting blood circulation on the clinical efficacy and quality of life of CKD stage 3 patients with kidney deiciency and blood stasis type.Methods:A prospective,randomized,controlled study was conducted,100 patients with CKD stage 3 with'kidney deficiency and blood stasis'were randomly divided into the observation group(50 cases)and the control group(50 cases).The control group was given basic Chinese and Western medicine treatment,and the observation group was combined with chronic disease management programs,with an observation period of 24 weeks.Results:Compared with the pre-treatment period of this group,the TCM evidence points of both groups were significantly lower after 12 and 24 weeks of treatment(P＜0.05);at 24 weeks of treatment,the TCM evidence points of the observation group were significantly lower than those of the control group during the same period(P＜0.01).The serum creatinine and urea nitrogen of patients in the observation group after 12 and 24 weeks of treatment were significantly lower than before treatment(P＜0.05,P＜0.01),and eGFR was significantly increased compared with the previous treatment(P＜0.05,P＜0.01),and significantly better than the control group in the same period(P＜0.05);after 24 weeks of treatment,the 24-hour urine protein quantification of patients in the observation group was significantly lower than before treatment(P＜0.01),and significantly lower than the control group in the same period(P＜0.05).Albumin was significantly increased compared with the previous treatment(P＜0.05),and significantly higher than the control group in the same period(P＜0.05).In terms of life quality,the scores of all dimensions of patients in the observation group after 12 and 24 weeks of treatment were significantly higher than those before treatment(P＜0.05,P＜0.01)and were significantly higher than the control group at 24 weeks(P＜0.05,P＜0.01).Conclusion:The chronic disease management pattern based on'tonifying kidney and promoting blood circulation'has good clinical efficacy for CKD stage 3 patients with kidney deiciency and blood stasis type,which can improve the quality of life of patients,and is safe and reliable,worthy of clinical promotion.
Tonifying kidney and promoting blood circulationSyndrome of kidney deficiency and blood stasisChronic kidney disease(CKD)CKD stage 3Chronic disease managementClinical study
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NSTL
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