Prospective cohort study on the impact of traditional Chinese medicine constitution on readmission of patients with myocardial infarction
Objective:To explore the influence of traditional Chinese medicine(TCM)constitution on readmission of patients with myocardial infarction(MI).Methods:MI patients were enrolled using a prospective study method,and were divided into readmission and non-readmission groups according to whether readmission occurred within 1 year of follow-up,and the TCM constitution and clinical information of the two groups were counted at baseline.TCM constitution and clinical data with statistically significant differences were included in logistic regression equations to analyze the risk factors for patient readmission,and the predictive value of the regression model and risk factors was evaluated using the receiver operating characteristic curve(ROC).Results:A total of 277 patients were enrolled,and 242 patients reported whether or not they were readmitted to the hospital within 1 year of follow-up,including 49 in the readmission group.In terms of TCM constitution,242 patients were predominantly qi deficiency constitution,blood stasis constitution,and yang deficiency constitution.The 2 groups had significant differences in qi deficiency constitution,blood stasis constitution,phlegm dampness constitution,gentleness constitution,CCS grading,reconstruction therapy,nitrate therapy,poor sleep,and poor appetite(P＜0.05).The risk of readmission was significantly higher for those who were qi deficiency constitution,blood stasis constitution,phlegm-dampness constitution,not gentleness constitution,did not undergo reconstruction therapy,treated with nitrates,had a CCS classification ≥ Ⅱ,had poor sleep,and poor appetite.The results of the Logistic regression analyses showed that,after correction for multifactorial factors,the risk of readmission for qi deficiency constitution was 2.53 times higher than that of non-qi deficiency constitution(95％CI[1.05,6.12],P＜0.05).The ROC curves were plotted according to the predicted values of the regression model and qi deficiency constitution,and the AUC of the regression model=0.77 and the AUC of qi deficiency constitution=0.67,with a significance level(P＜0.05).Conclusion:Qi deficiency constitution is an independent risk factor affecting readmission of MI patients,and special attention should be paid to this group of patients in the early stages and effective preventive strategies should be adopted in time to reduce the readmission rate.
Traditional Chinese medicine constitutionMyocardial infarctionReadmissionInfluencing factorsLogistic regression
NETL
NSTL
万方数据
