Renal involvement in primary Sjögren's syndrome(RISS)is one of the common complications in the middle and late stage of primary Sjögren's syndrome and its treatment is quite difficult in clinical practice.Combined with the pathogenesis and pathological characteristics of the disease,under the guidance of the theory of traditional Chinese medicine,based on the theory of'turbid yin'in Huangdi Neijing,this paper tries to discuss that the core pathogenesis of RISS is turbid yin disorder,including turbid yin failing to fall,failing to transform and failing to pass.The treatment principle of the disease to lower,transform,and unblock turbid yin is established,hoping to provide some new ideas and methods for the prevention and treatment of the disease.