Objective:To observe the clinical efficacy of Wenfei Prescription in the treatment of eosinophilic chronic rhinosinusitis with nasal polyps after operation and its effect on related inflammatory factors interleukin(IL)-13,IL-33 and immunoglobulin E(IgE).Methods:A total of 92 patients with ECRSwNP of lung qi deficiency and cold type were randomly divided into control group and observation group,with 46 cases in each group.After endoscopic sinus surgery,the control group was treated with mometasone furoate nasal spray.The observation group was given self-made Wenfei Prescription on the basis of the control group.After 2 courses of treatment,the changes of TCM syndrome score,VAS score,nasal endoscopy score,related inflammatory factor content and postoperative recurrence rate were observed before and after treatment.Results:After treatment,the TCM syndrome score,VAS score,nasal endoscopy score and related inflammatory factor levels in two groups were significantly lower than those before treatment(P＜0.05),and the observation group was better than the control group(P＜0.05).The recurrence rate in the observation group was significantly lower than that in the control group(P＜0.05).Conclusion:Wenfei Prescription can promote the recovery of nasal mucosa and cilia function,improve the symptoms of patients and reduce the recurrence rate of patients after ECRSwNP by regulating the level of inflammatory factors and adjusting the immune function of the body.
Eosinophilic chronic rhinosinusitis with nasal polypsWenfei PrescriptionInflammatory factorsImmunoglobulin E(IgE)Clinical efficacy
NETL
NSTL
万方数据
