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《金匮要略》论治肝癌瘀毒互结证发微

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瘀毒互结是肝癌发生发展的关键病机之一,化瘀解毒是治疗肝癌瘀毒互结证的核心治法之一,但单一的化瘀解毒法论治临床上错综复杂的肝癌是不够全面的,笔者通过对肝癌的主要症状及并发症状的研究,援用《金匮要略》中相关条文背后的理法方药对肝癌论治进行探讨,总结出了肝癌瘀毒互结证的四大治疗思路,分别为"护肝体,调补肝阴而不致瘀""调肝脾,防传变而平五脏""化瘀解毒,清实邪以达肝用""治兼证,顾全局以合病机",以期为肝癌瘀毒互结证的中医论治提供理论依据.
Elucidation on the Synopsis of the Golden Chamber in the treatment of liver cancer with the blood-stasis-toxin syndrome
The combination of blood stasis and toxin is one of the key pathological mechanisms for the occurrence and development of liver cancer.Resolving blood stasis and detoxification is one of the core treatment methods for treating the syndrome of blood-stasis-toxin in liver cancer.However,a single method of resolving blood stasis and detoxification is not comprehensive enough to treat the complex clinical liver cancer.Through the study of the main symptoms and concurrent symptoms of liver cancer,the author uses the relevant provisions in the Synopsis of the Golden Chamber to explore the treatment of liver cancer based on the principles,laws,and medicines,four treatment strategies for liver cancer with the syndrome of blood-stasis-toxin have been summarized,namely'protecting the liver body,regulating and supplementing liver yin without causing blood stasis','regulating the liver and spleen,preventing transmission of changes and calming the five organs','resolving blood stasis and detoxification,clearing excess evil to achieve liver function',and'treating symptoms,considering the overall situation to include the pathogenesis',in order to provide theoretical basis for the traditional Chinese medicine treatment of liver cancer with the syndrome of blood-stasis-toxin.

Blood-stasis-toxin syndromeLiver cancerSynopsis of the Golden ChamberTreatment strategiesResolving blood stasis and detoxification

吴含章、王伟雄、林艳巧、姜涛、张光霁

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浙江省中医"瘀毒"证重点实验室,杭州 310053

中医"治未病"智慧健康浙江省工程研究中心,杭州 310053

霞浦县医院,宁德 355100

浙江中医药大学基础医学院,杭州 310053

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瘀毒互结证 肝癌 《金匮要略》 治疗思路 化瘀解毒

国家自然科学基金面上项目

81874455

2024

中华中医药杂志
中华中医药学会

中华中医药杂志

CSTPCD北大核心
影响因子:1.135
ISSN:1673-1727
年,卷(期):2024.39(7)
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