Discussion on the treatment of lung cancer based on iron death from the'yin qi and yang qi circulating out of order'
Iron death is a newly discovered form of cell death,and numerous studies have shown that using iron death as a target in the treatment of lung cancer has great potential.The concept of'yin qi and yang qi circulating out of order'comes from Treatise on Febrile Diseases.Professor LI Zhong proposed that the pathogenesis of lung cancer is based on the concept of'yin qi and yang qi circulating out of order'.The depletion of health qi is an intrinsic factor in the progression of lung cancer and is crucial;endogenous cancer toxin is an external manifestation of lung cancer pathogenesis and a direct influencing factor.The mechanism of iron death in lung cancer is interconnected with the phenomenon of'yin qi and yang qi circulating out of order'.Iron death has both pro tumor and anti tumor regulatory effects in the progression of lung cancer.The dissipation of health qi cannot induce ferroptosis in lung malignant tumor cells,and its anti-tumor effect is weakened.The tumor promoting effect of tangible cancer toxin on inducing ferroptosis in lung malignant tumor cells is enhanced.The dissipation of health qi is combined with endogenous cancer toxins,causing iron death in lung cancer cells to develop in an unfavorable direction,leading to the progression of lung cancer.Therefore,in the treatment,it is crucial to attach importance to the consolidation method of strengthening qi and cancer toxin based on syndrome differentiation and treatment.
Iron deathLung cancerYin qi and yang qi circulating out of orderConsolidation method
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