基于文献探讨国医大师洪广祥治疗慢性阻塞性肺病经验

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中文摘要：目的:通过对小青龙汤加减治疗慢性阻塞性肺病(COPD)急性期的临床试验类文献进行数据统计分析,探讨洪广祥学术思想的循证医学证据.方法:检索常用数据库中国知网(CNKI)、万方中国学术期刊数据库(COJ)、维普中文期刊(VIP-CSTJ)、Cochrane数据库、PubMed数据库、中国生物医学文献数据库(CBM)收录的小青龙汤治疗COPD急性期的临床试验类文献,通过NoteExpress剔除重复文献,依据纳排标准筛选文献,数据提取至Excel表格,着重对加减药物进行总结统计分析.结果:共纳入103篇文献,小青龙汤加减治疗COPD急性期效果、治疗后肺功能及动脉血气指标均优于单一西医治疗.明确小青龙汤加减治疗的文献有62篇,加味药物共有43味中药,用药情况分析表明,具有"温"作用的药物和具有"治气"作用的药物在加味药物中占有较高比例,与洪广祥学术观点吻合.结论:小青龙汤加减治疗COPD急性期能够显著提高临床治疗总有效率和改善肺功能.洪广祥辨治COPD经验为治疗提供了有价值的中医药治疗方案和理论依据,并且加味药物的使用体现了洪广祥学术思想的精髓.

外文标题：Discussion on TCM master HONG Guangxiang's experience in treatment of chronic obstructive pulmonary disease based on the literatures

外文摘要：Objective:To investigate the evidence-based medical support for professor HONG Guangxiang's academic insights by statistically analyzing clinical trials on the application of modified Xiaoqinglong Decoction(XQLD)for the treatment of acute exacerbations of chronic obstructive pulmonary disease(COPD).Methods:The comprehensive literature search was performed in frequently utilized databases,including the China National Knowledge Infrastructure(CNKI),China Online Journals(COJ),VIP-CSTJ,the Cochrane Library,PubMed,and the China Biological Medicine Database(CBM),to identify clinical trial articles pertaining to the application of modified XQLD in the treatment of acute exacerbations of COPD.Duplicate articles were eliminated using NoteExpress software,and the remaining literature was screened according to pre-defined inclusion and exclusion criteria.Relevant data were extracted and organized into an Excel spreadsheet for detailed analysis,with a specific emphasis on summarizing and statistically analyzing the modifications made to the herbal prescriptions.Results:A total of 103 papers met the inclusion criteria.The efficacy of XQLD modifications in treating acute exacerbations of COPD,as well as improvements in pulmonary function and arterial blood gases,were found to be superior to conventional Western medical therapy alone.There were 62 pieces of literature that clearly described the modified treatment of XQLD,involving 43 different Chinese medicinal herbs.The analysis of herbal-medicine revealed a higher proportion of those with'warming'properties and those aimed at'regulating qi',which aligns with the principles advocated by professor HONG Guangxiang.Conclusion:The use of modified XQLD in the treatment of acute exacerbations of COPD significantly enhances clinical outcomes and pulmonary function.Professor HONG Guangxiang's diagnostic and therapeutic experience in treating COPD offers valuable traditional Chinese medicine treatment plans and theoretical foundations.Moreover,the application of modified medicinal herbs reflects the essence of HONG Guangxiang's academic philosophy.

外文关键词：

Xiaoqinglong DecoctionChronic obstructive pulmonary disease(COPD)Data miningClinical curative effectHONG GuangxiangLiterature researchEvidence-based supportModified medicinal herbs

作者：

肖芳宝、柯诗文、刘良徛

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作者单位：

江西中医药大学,南昌 330006

江西中医药大学附属医院肺病科,南昌 330006

关键词：

小青龙汤慢性阻塞性肺病数据挖掘临床疗效洪广祥文献研究循证证据加味药

基金：

国医大师洪广祥全国名老中医药专家传承工作室国家自然科学基金项目江西省科技厅重点研发计划江西省自然科学基金项目江西省自然科学基金项目江西省教育厅科学技术研究项目江西省卫生健康委科技计划项目江西省中医药管理局科技计划项目江西省肺系疾病临床医学研究中心江西省中医肺病学重点实验室江西中医药大学科技创新团队建设项目

项目编号：

国中医药人教发[2014]20号8230516220232BBG7002120212BAB21606120232BAB206145GJJ2112492022107832022B24820181BCG42005赣科发财字[2015]142号CXTD22011

出版年：

2024

中华中医药杂志

中华中医药学会

中华中医药杂志

CSTPCD北大核心

影响因子：1.135

ISSN：1673-1727

年,卷(期)：2024.39(7)

参考文献量11