Research progress of functional magnetic resonance imaging on acupuncture intervention for Alzheimer's disease
Acupuncture serves as a potent therapeutic modality for managing Alzheimer's disease(AD),and functional magnetic resonance imaging(fMRI)provides objective insights into the central mechanisms by which acupuncture exerts its effects.This paper reviewed the fMRI studies on acupuncture for AD in the past decade,and summarized the study design,analysis method and response brain region/networks.It was found that low-frequency amplitude and seed-point functional connectivity methods were used in resting fMRI to observe brain function changes after acupuncture,and task fMRI was used to observe brain region activation during acupuncture stimulation.The response brain regions included cingulate gyrus,inferior frontal gyrus,middle frontal gyrus,superior frontal gyrus,middle temporal gyrus,etc.The response brain networks include the default mode network,frontoparietal network and visual network.However,the study design of current fMRI studies on acupuncture for AD is relatively straightforward,and the analysis methods are quite limited,need to be expanded to further explore the central mechanism of acupuncture intervention in AD.It is still necessary to broaden research strategies to gain a more comprehensive understanding of the underlying central mechanisms of acupuncture in the treatment of AD.
AcupunctureFunctional magnetic resonance imaging(fMRI)Alzheimer's diseaseReviewAnalysis methodsResponse brain regions
NETL
NSTL
万方数据
