针灸治疗早发性卵巢功能不全临床研究设计的思考:从随机对照试验到真实世界研究
Consideration on clinical research design of acupuncture in the treatment of premature ovarian insufficiency:From randomized controlled trial to real world study
郑晨思 1勾明会 2叶海腾 1杨会生 1蔡贤兵1
作者信息
- 1. 深圳市妇幼保健院,深圳 518000
- 2. 首都医科大学附属北京妇产医院,北京 100020
- 折叠
摘要
目的:总结分析对比针灸治疗早发性卵巢功能不全(POI)现有的临床研究设计,为找到更科学、可行性更高的研究设计方法提供思路.方法:根据纳入排除标准进行文献检索、将临床研究进行分类、提取研究要素进行总结分析.结果:纳入分析的12篇文献中,有9篇随机对照试验(RCT),3篇真实世界研究(RWS),分别分析两种研究方法的特征、优势和存在的问题.结论:综合运用RCT和RWS的方法开展临床研究,才能更好地为针灸治疗POI提供更科学、更有力的临床证据.
Abstract
Objective:To summarize,analyze and compare the existing clinical research designs of acupuncture and moxibustion in the treatment of premature ovarian insufficiency(POI),so as to provide ideas for finding a more scientific and feasible research design method.Methods:According to the inclusion and exclusion criteria,the literature was searched,the clinical studies were classified,and the research elements were extracted for summary analysis.Results:A total of 12 articles were included in the analysis,including 9 randomized controlled trials(RCT)and 3 real-world studies(RWS).The characteristics,advantages and problems of the two research methods were analyzed.Conclusion:The comprehensive use of RCT and RWS in clinical research can provide more scientific and powerful clinical evidence for acupuncture and moxibustion in the treatment of POI.
关键词
早发性卵巢功能不全/针灸/随机对照试验/真实世界研究Key words
Premature ovarian insufficiency(POI)/Acupuncture/Randomized controlled/Real word research引用本文复制引用
基金项目
广东省中医药局科研项目(20221344)
出版年
2024
国家科技期刊平台
NSTL
万方数据