HIV/AIDS中医证候研究现况与展望
Current status and prospect of the traditional Chinese medicine syndrome of HIV/AIDS
宋夕元 1马秀霞 2孟鹏飞 1刘梅君 3金书情 3唐洲 3徐立然 1郭会军1
作者信息
- 1. 河南中医药大学第一附属医院,郑州 450000;河南中医药大学,郑州 450046;河南省病毒性疾病中医药防治重点实验室,郑州 450000
- 2. 河南中医药大学第一附属医院,郑州 450000;河南省病毒性疾病中医药防治重点实验室,郑州 450000
- 3. 河南中医药大学,郑州 450046
- 折叠
摘要
HIV/AIDS是复杂疑难性疾病,目前尚无有效的治愈方法.HIV/AIDS证候是辨证施治的核心,开展证候演变规律及物质基础研究是探索证候实质、筛选药物作用靶点、研发有效方剂、提高临床疗效关键环节.笔者通过梳理HIV/AIDS证候研究现况及临床实践,总结出了HIV/AIDS证候以兼夹证为主,证候呈现"虚进实渐"的演变规律,即实证-虚证-虚实夹杂证-虚衰证-衰竭证的病理过程.通过分析系统生物学在HIV/AIDS虚证及实证的应用,阐述了证候研究存在的问题,提出了对策及展望,旨在为相关研究提供参考.
Abstract
HIV/AIDS is a complex and difficult disease,and no effective method of cure is available at present.HIV/AIDS syndrome is the core of syndrome differentiation.Studying the evolvement law and physical basis of the syndrome is a key link to exploring the essence of the syndrome,screening out drug targets,developing effective prescriptions and improving clinical efficacy.By combing the current status and prospect of HIV/AIDS syndrome studies and clinical practice,the author summarizes that HIV/AIDS syndrome is dominated by concurrent syndrome and presents an'excess-mix of excess and deficiency-deficiency'dynamic evolvement law.That is,the pathological process of excess syndrome-deficiency syndrome-deficiency and excess mixed with syndrome-deficiency and failure syndrome-failure syndrome.Besides,the paper analyzes the application of systems biology in HIV/AIDS deficiency syndrome and excess syndrome,elaborates on the problems in existing syndrome research,and puts forward countermeasures and prospects,with an aim to provide a reference for related research.
关键词
HIV/AIDS/证候演变规律/免疫学指标/系统生物学/展望Key words
HIV/AIDS/Evolvement law of syndrome/Immunologic indicators/Systems biology/Prospect引用本文复制引用
基金项目
国家"十三五"科技重大专项(2017ZX10205502)
河南省中医药科学研究专项课题(2021JDZY001)
河南省自然科学基金项目(232300420274)
河南省"双一流"创建学科中医学科学研究专项(HSRP-DFCTCM-2023-8-03)
出版年
2024
NETL
NSTL
万方数据