Discussion on etiology and pathogenesis of henoch-sch?nlein purpura in children based on the theory of'five-Zang organs corresponding to the seasons'
Combination of internal and external pathogens serves as the main cause of henoch-schönlein purpura in children.Different qi in the four seasons corresponds with different Zang-organs;different pathogens in seasons can also lead to different etiologies and pathogenesis.In spring,its pathogenesis may be latent pathogens induced by external pathogens,or the combination of external pathogens and liver fire,or the invasion of collaterals by wind pathogen.On treatment,the ascending property should be followed to usher latent pathogens.Meanwhile,drugs in cold or cool property should be avoided in case suppressing the liver qi.Besides,methods of expelling wind and dispelling pathogens should be considered.In summer,its pathogenesis may be exuberance of qi damaging the collaterals,or heat pathogen entering the blood aspect,or qi failing to securing blood.The treatment strategy concludes clearing heat and descending qi,and cooling the blood and nourishing yin,with the consideration of promoting the blood circulation and removing blood stasis.In autumn,its pathogenesis may be that the pathogens of dampness and heat are suppressed by the descending qi,or the external pathogens invading the defense,or the dry pathogen damaging the body fluid with stagnated blood damaging the collaterals.The main treatment principles include clearing and diffusing latent pathogens,boosting qi and nourishing yin,together with moisturizing dryness.In winter,the pathogenesis may be closing of muscular interstices and no dispersion of heat,or external pathogens attacking the kidneys,or cold pathogen residing in the collaterals.On treatment,the property of sealing should be followed to avoid other pathogens affecting the kidneys,so that,the balance of yin and yang in the kidneys can be restored.Meanwhile,the dispersion of the wind and cold pathogens should be considered.In addition,the spleen corresponds to later summer,governs its transport and transformation as well as the four seasons.Protection of the spleen and stomach should bear in mind in all seasons.Diagnosis and treatment of henoch-schönlein purpura in children based on the theory of five-Zang organs corresponding to the seasons takes into account not only human factors,but also the factors of the heaven,reflecting the thought of'knowing astronomy in heaven,geography on earth,and human affairs'in the chapter of Discussion on the Changes of Qi-Convergence in Plain Questions.
Henoch-schönlein purpura in childrenFive-Zang organs corresponding to the seasonsCorrespondence between human and natureEtiology and pathogenesisTreatment based on different seasons
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