中医药抗氧化应激提高精子质量的机制研究进展
Research progress on the mechanism of traditional Chinese medicine against oxidative stress to improve sperm quality
魏超峰 1相珊 1连方2
作者信息
- 1. 山东中医药大学第一临床医学院,济南 250355
- 2. 山东中医药大学附属医院,济南 250011
- 折叠
摘要
由于环境污染、食品安全、不良生活习惯等多种因素,男性精子质量不断下降.研究表明,氧化应激是导致精子质量下降的一个重要原因,它可以破坏精子膜结构、损伤精子染色质、增加细胞凋亡,从而影响精子的质量和功能.且精子对氧化应激特别敏感,而自身抗氧化能力弱,需要通过多种方式来增强抗氧化能力.中医药抗氧化应激的功效得到了广泛认可,在生精养精、改善精子质量方面具有独特优势.文章就近5年国内外基于氧化应激探究中医药改善精子质量的研究进行综述,以期为临床实践提供依据,为解决男性精子质量下降这一严峻问题提供些许思路.
Abstract
Due to a variety of factors such as environmental pollution,food safety,and poor living habits,the quality of male sperm continues to decline.Research shows that oxidative stress is an important cause of sperm quality decline,which can destroy sperm membrane structure,damage sperm chromatin,increase apoptosis,thus affecting the quality and function of sperm.Moreover,spermatozoa are particularly sensitive to oxidative stress,and their own antioxidant capacity is weak,so they need to be enhanced in various ways to enhance their antioxidant capacity.The efficacy of traditional Chinese medicine(TCM)against oxidative stress has been widely recognized,and it has unique advantages in spermatogenesis and sperm nourishment,and improving sperm quality.In this paper,we review the research on improving sperm quality by TCM based on oxidative stress in the past five years,with a view to providing a basis for clinical practice and some ideas for solving the serious problem of declining sperm quality in men.
关键词
中医药/中药单体/氧化应激/抗氧化/精子质量Key words
Traditional Chinese medicine/Chinese medicine monomers/Oxidative stress/Antioxidant/Sperm quality引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据