Prospective cohort study on dynamic characteristics of elderly frailty and the intervention of traditonal Chinese and Western medicine
Objective;To explore the clinical value of the combination of traditional Chinese and Western medicine intervention in the elderly frailty.Methods:By convenient sampling method,elderly patients who visited the Department of Traditional Chinese Medicine in each general hospital in seven urban areas of Beijing from January to December 2021 were selected as the research objects,divided into two groups(Western medicine group and integrated Chinese and Western medicine group),and their frailty index was followed up dynamically(a total of 4 times).Results:A total of 774 observation subjects were included in this study,including 278 in the Western medicine group and 496 in the integrated Chinese and Western medicine group.Results of the first follow-up:a total of 113 cases had no asthenia,204 cases had preasthenia and 457 cases had asthenia.The incidence of preasthenia and asthenia were 26.36％and 59.04％,respectively.According to the results of the first follow-up,the frailties were divided into the non-frailties group,the pre-frailties group and the frailties stage group.The frailties of the fourth follow-up were the outcome:in the non-frailties group,73.25％cases maintained the status,24.78％cases and 1.77％cases progressed to the pre-frailties and the frailties stage,respectively.In the pre-asthenic group,37.25％cases maintained the state,39.22％cases reversed to no asthenic stage,and 23.53％cases progressed to asthenic stage.In the asthenic stage group,73.52％cases maintained the state,25.16％cases and 1.31％cases reversed to pre-asthenic stage and non-asthenic stage,respectively.The number of non-fthenic patients at the fourth follow-up was higher than that at the first follow-up,the number of patients in the pre-fthenic period had no significant change,and the number of patients in the fthenic period was lower than that at the first follow-up.In the Western medicine group,the number of patients without fadility at the fourth follow-up was lower than that at the first follow-up,there was no significant change in the pre-fadility period,and the number of patients at fadility period was higher than that at the first follow-up.The frailties index in the second,third and fourth follow-up were lower than those in the first follow-up(P＜0.01).Repeated measurement results showed that with the increase of evaluation times,the fthenicity index of integrated Chinese and Western medicine group decreased gradually(P＜0.05).Chi-square test showed that the effective rate of integrated Chinese and Western medicine group was higher than that of Western medicine group[95.97％(476/496)vs 79.14％(220/278)](P＜0.05).The results of binary Logistic regression model suggested that the combination of traditional Chinese and Western medicine(OR=7.429,95％CI[4.121～13.392],P=0.000)was an effective means of fasticity intervention.Conclusion:The early stage of asthenia is unstable,which is the best entry point for intervention.Compared with simple western medicine intervention,the combination of traditional Chinese and Western medicine can effectively improve the debilitation situation.
Elderly frailtyTraditional Chinese and Western medicineInterventionDynamicFrailty assessment
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NSTL
万方数据
