Discussion on the pathogenesis of'deficiency-toxicity'interaction of malignant tumors and differentiation and treatment from the perspective of immunoediting
Based on the theory of'five-stage evolution',this paper explores the biological basis of the interaction between'deficiency-toxicity'in the pathogenesis of malignant tumors from the perspective of immunoediting,that is,'qi deficiency and insolidity'focuses on the weakening of immune clearance,'yang deficiency and poison nodules'are associated with increased immune remodeling,and'cancer toxicity infusion'is manifested as the stemness of cancer cells induced by tumor microenvironment,and cancer toxicity further harms the healthy qi,and the'deficiency-toxicity'interaction leads to the positive loss of toxicity.In summary,combined with the'five methods of strengthening vita qi'put forward by our team,the author summarizes and proposes the diagnosis and treatment ideas of invigorating qi and strengthening and gaining immune clearance and regulation of'deficiency',inhibiting immune remodeling and truncating'cold'by inhibiting temperature and yang,detoxifying and reversing the stemness inhibition of tumor cells,and anchoring the dominant stage of immune editing traditional Chinese medicine intervention,combining syndrome differentiation drugs with precise target drugs,and corroborating evidence to test prescriptions,in order to provide a certain reference for clinical practice.
Immunoediting'Deficiency-toxicity'interactionMalignant tumorsFive-stage evolutionFive methods of strengthening vita qiEtiology and pathogenesisTreatment based on pattern differentiation