Research progress on metabolomics of insomnia treated by traditional Chinese medicine
Insomnia is a common clinical sleep disorder,which seriously affects daily life.Traditional Chinese medicine(TCM)has unique advantages in the treatment of insomnia because of its multi-pathway and multi-target.Metabolomics can identify the pharmacodynamic material basis and related phenotypic changes because of its screening biomarkers through the changes of endogenous metabolites,which can provide strong support for the study of TCM intervention in insomnia.Metabolomics is consistent with the overall concept of TCM and the thinking mode of syndrome differentiation and treatment,and can be used as an objective and effective means to clarify the syndrome type and the target of TCM.In this paper,the research progress of potential metabolic markers and metabolic pathways of TCM in the treatment of insomnia will be expounded from the aspects of metabolomics,TCM syndromes and therapeutic targets of TCM,and the metabolic pathways of TCM in the treatment of insomnia will be summarized,so as to provide reference for further research and clinical application.
InsomniaMetabolomicsSyndromeTraditional Chinese medicineBiomarkersTherapeutic targetsProgress
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万方数据
