Research advances of antibiotics on multidrug-resistant Pseudomonas aeruginosa infections
Multidrug-resistant Pseudomonas aeruginosa has become one of the common pathogens of nosocomial infections.It can simultaneously develop resistance to common antibiotics through multiple resistance mechanisms.Increasing treatment difficul-ties and patient mortality significantly,it has become a global public health challenge.This review focused upon the epidemiologi-cal features and risk factors of Pseudomonas aeruginosa infection,the resistance characteristics to commonly used antibiotics and analyzes the sensitivity criteria and clinical applications of new antibiotics against multidrug-resistant Pseudomonas aeruginosa including ceftolozane/tazobactam,ceftazidime/avibactam,imipenem-cilastatin/relebactam and cefiderocol.It may provide refer-ences for clinical applications.
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