Evaluation criteria of ziprasidone for injection and analysis of its application results based upon TOPSIS method
OBJECTIVE To establish the drug use evaluation(DUE)criteria for ziprasidone for injection based upon tech-nique for order preference by similarity to an ideal solution(TOPSIS)method for evaluating the rationality of its clinical use.METHODS Based upon the drug instructions of Ziprasidone for injection,the DUE standard for ziprasidone for injection was established by referring to the relevant guidelines and expert consensus through consultations.Also weighted TOPSIS method was employed for retrospectively reviewing the archived cases of ziprasidone for injection at Anhui Mental Health Center from January to December 2022 for rationality evaluation.RESULTS A total of 269 cases were included and only 31(11.52％)fully fulfilled the evaluation criteria.Irrational use of ziprasidone for injection was common in off-label(46.47％),contraindications(0.37％),dosing course(9.29％),auxiliary and laboratory examinations(32.71％),drug interaction(13.01％),special popu-lation(2.97％)and drug sequence(7.06％).CONCLUSION The established ziprasidone for injection DUE standard may be used for clinical use of ziprasidone for injection.
ziprasidone for injectionvaluation criteria for drug utilizationrational drug useexpert consultation methodweighted TOPSIS method
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