医药用自愈性水凝胶性能和载体研究进展
Research advances on properties and carriers of self-healing hydrogels for medical applications
刘铭 1文武龙 1张炜烨 1杨婧 2王锐1
作者信息
- 1. 黑龙江中医药大学药学院,黑龙江哈尔滨 150040
- 2. 黑龙江中医药大学基础医学院,黑龙江哈尔滨 150040
- 折叠
摘要
自愈性水凝胶是一种具有网状结构,拥有自我修复能力的一种新型材料.这种材料一方面具有本征性的自愈性,通过动态化学键实现结构断裂后重新连接.另一方面,水凝胶具有动态的自我调节性以及生物相容性,是极具潜力的药物递送载体.该文综述了基于自愈性水凝胶在药物递送领域的研究进展,探讨了自愈性水凝胶的载药系统在药剂学的应用前景和研究方向.
Abstract
Self-healing hydrogel is a novel type of material with reticular structure and self-healing capability.On the one hand,this material has intrinsic self-healing and realizes its self-healing property of structural fracture and reconnection through dynamic chemical bonding.On the other hand,hydrogels are dynamic,self-regulating and biocompatible,making them promising drug delivery vehicles.This review summarized the latest researches of self-healing hydrogels in the field of drug delivery.Also application prospects and research directions of drug-loading systems based upon self-healing hydrogels in pharmacy were discussed.
关键词
自愈性水凝胶/载体工程/靶向/给药系统Key words
self-healing hydrogels/carrier engineering/targeting/drug delivery system引用本文复制引用
基金项目
国家自然科学基金(82074271)
国家自然科学基金资助项目(81603418)
出版年
2024
NETL
NSTL
万方数据