Infantile liver injury aggravated by iron protein-succinylate:one case report
ABSTRACT:Anemia is one of common complication in patients with chronic kidney disease.Iron supplement is a standard treatment for renal anemia.Liver is a major site of iron storage.Growing evidence suggests that long-term iron therapy is associated with a risk of hepatic iron overload.This report described one infant with aggravated liver injury after dosing of iron protein succinylate.It elucidated the mecha-nism by which iron overload causes liver damage and liver fibrosis through inducing ferroptosis.It provides a warning for long-term application of iron in the treatment of anemia in the future.
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