Research advances on the treatment of periodontitis with topical oral drug delivery
As an inflammatory disease caused by microorganisms,periodontitis affects the surrounding tissues of teeth and ulti-mately leads to a destruction of alveolar bone and tooth loss.Systemic and local periodontal treatments,selecting appropriate anti-bacterial drugs and a proper dosing route are crucial factors for treating periodontitis.Local oral drug delivery offers high safety and significant efficacy and it is a promising drug delivery strategy.This review summarized the characteristics of periodontitis,its pathogenesis and oral mucosal drug delivery systems.
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